Effects of speckle/pixel size ratio on temporal and spatial speckle-contrast analysis of dynamic scattering systems: Implications for measurements of blood-flow dynamics.
نویسندگان
چکیده
Laser Speckle Contrast Imaging (LSCI) is an optical technique used to generate blood flow maps with high spatial and temporal resolution. It is well known that in LSCI, the speckle size must exceed the Nyquist criterion to maximize the speckle's pattern contrast. In this work, we study experimentally the effect of speckle-pixel size ratio not only in dynamic speckle contrast, but also on the calculation of the relative flow speed for temporal and spatial analysis. Our data suggest that the temporal LSCI algorithm is more accurate at assessing the relative changes in flow speed than the spatial algorithm.
منابع مشابه
Dynamic laser speckle imaging of cerebral blood flow.
Laser speckle imaging (LSI) based on the speckle contrast analysis is a simple and robust technique for imaging of heterogeneous dynamics. LSI finds frequent application for dynamical mapping of cerebral blood flow, as it features high spatial and temporal resolution. However, the quantitative interpretation of the acquired data is not straightforward for the common case of a speckle field form...
متن کاملSpeckle Reduction in Synthetic Aperture Radar Images in Wavelet Domain Exploiting Intra-scale and Inter-scale Dependencies
Synthetic Aperture Radar (SAR) images are inherently affected by a multiplicative noise-like phenomenon called speckle, which is indeed the nature of all coherent systems. Speckle decreases the performance of almost all the information extraction methods such as classification, segmentation, and change detection, therefore speckle must be suppressed. Despeckling can be applied by the multilooki...
متن کاملSimple correction factor for laser speckle imaging of flow dynamics.
One of the major constraints facing laser speckle imaging for blood-flow measurement is reliable measurement of the correlation time (τ(C)) of the back-scattered light and, hence, the blood's speed in blood vessels. In this Letter, we present a new model expression for integrated speckle contrast, which accounts not only for temporal integration but spatial integration, too, due to the finite s...
متن کاملSpatial versus temporal laser speckle contrast analyses in the presence of static optical scatterers.
Previously published data demonstrate that the temporal processing algorithm for laser speckle contrast imaging (LSCI) can improve the visibility of deep blood vessels and is less susceptible to static speckle artifacts when compared with the spatial algorithm. To the best of our knowledge, the extent to which the temporal algorithm can accurately predict the speckle contrast associated with fl...
متن کاملQuantitative, depth-resolved determination of particle motion using multi-exposure, spatial frequency domain laser speckle imaging.
Laser Speckle Imaging (LSI) is a simple, noninvasive technique for rapid imaging of particle motion in scattering media such as biological tissue. LSI is generally used to derive a qualitative index of relative blood flow due to unknown impact from several variables that affect speckle contrast. These variables may include optical absorption and scattering coefficients, multi-layer dynamics inc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Biomedical optics express
دوره 4 10 شماره
صفحات -
تاریخ انتشار 2013